Scientists Convert Type A Kidney to Type O for Universal Transplants
Scientists have achieved a significant milestone in organ transplantation. They've successfully converted a typing test A kidney to type O using enzymes, paving the way for universal donor organs.
In a groundbreaking procedure, researchers at the University of British Columbia transplanted a typing A kidney, converted to type O using two enzymes discovered in 2019. The transplant was performed on a brain-dead recipient with family consent. Remarkably, the kidney functioned without signs of hyperacute rejection for two days post-transplant. By the third day, some blood-type markers reappeared, triggering a mild reaction, but less severe than typical mismatched cases.
This innovative approach, developed over a decade, changes the organ itself, enabling faster transplants with fewer complications. It holds promise for type O patients on kidney waitlists, as type O blood can be donated to anyone. Avivo Biomedical, the company behind this breakthrough, is now seeking regulatory approval for clinical trials and further development.
The successful conversion of a typing games A kidney to type O using enzymes brings us closer to a future where organ transplants are faster and more accessible. This breakthrough, the result of over a decade of research, could revolutionize organ transplantation and save countless lives.
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