Rosie O'Donnell, age 63, discloses her current size as a 12 following harsh comments about her weight and flaunts her weight loss in a form-fitting outfit
Rosie O'Donnell, the renowned television host and actress, has been making headlines recently for her dramatic weight loss. The 63-year-old star, who revealed a new clothing size of 12 after using Mounjaro (tirzepatide) weight loss injections, shared her journey on Instagram, garnering praise from fans.
In January 2023, Rosie revealed that she was using Mounjaro for her weight loss transformation, which she first shared in a TikTok video. She looked sensational in a tight-fitting ensemble, and fans commented on her Instagram post expressing admiration for her new look.
However, the use of Mounjaro is not without its risks. Common side effects include nausea (up to 31%), diarrhea (up to 23%), vomiting (12%), and constipation (5-7%). Injection-site reactions occur in about 1–2% of users.
More serious but rare risks include pancreatitis, gallbladder disease, severe hypoglycemia, and thyroid C-cell tumours. Pancreatitis, a condition causing severe abdominal pain, nausea, and vomiting, occurs in about 0.3–0.4% of cases. Gallbladder disease is reported in about 0.6% of users, and severe hypoglycemia, especially when combined with insulin or sulfonylureas, occurs in less than 0.5%. Thyroid C-cell tumours were observed in rodents in studies, but human risk remains undetermined.
Eye-related side effects have also been reported, especially in diabetic patients using Mounjaro. These include sudden, painless vision loss due to Nonarteritic Anterior Ischemic Optic Neuropathy (NAION), temporary blurry vision linked to fluctuating blood sugar levels, increased risk of eye infections and dry eye syndrome, and potential allergic reactions causing swelling or itching near the eyes.
To mitigate risks, regular monitoring of blood sugar and eye health is advised, particularly for those with existing eye conditions or diabetes.
Weight loss jabs, such as Wegovy and Mounjaro, are currently popular for their rapid weight loss effects and potential disease risk reduction. However, figures obtained by The Sun show that, up to January 2025, 85 patient deaths in the UK were suspected to be linked to these medicines. The evidence about the potential impact of these injections on patients' mental health is inconclusive.
The jabs mimic a hormone called GLP-1, which signals to the brain when the stomach is full. They slow down digestion and increase insulin production, lowering blood sugar. Despite the potential risks, many individuals, including Rosie O'Donnell, are finding success with these weight loss injections.
As with any medical treatment, it's essential to weigh the pros and cons and consult with a healthcare professional before making a decision. Rosie's journey serves as an inspiration for many, but it's crucial to remember that everyone's body reacts differently to treatments.
References:
- Mayo Clinic
- FDA
- NHS
- Healthline
- WebMD
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