Cost, effects, applications, dosage, and additional details about Voranigo
Fresh, Original Version
Hey there! Let's dive into Voranigo, the brain tumor-busting badass.
If you've got a grade 2 astrocytoma or oligodendroglioma with a specific genetic mutation (IDH1 or IDH2), then Voranigo might be the solution you've been looking for. This bad boy is an isocitrate dehydrogenase-1 and isocitrate dehydrogenase-2 inhibitor, part of the targeted cancer therapy squad, and it's just the ticket for dealing with those stubborn tumors.
Worth noting, it's not available as a generic yet, homie. Don't expect any price drops from copycat medications just yet. A generic drug is essentially an exact duplicate of the active ingredient found in brand-name meds, generally coming in at a lower cost. But, as of now, Voranigo is only available as a brand-name medicine.
Now, the real question... how much will this set you back? As with all drugs, the cost can vary depending on factors like your insurance, location, and pharmacy. To help with the financial burden, a program called ServierONE is available for Voranigo users, which can provide copay cards to ease the financial strain. You can reach out at 800-813-5905 or visit the program website for more info on eligibility and support.
Beware, Voranigo can cause side effects, some of which can be serious. Common mild side effects include fatigue, headache, nausea, diarrhea, constipation, reduced appetite, muscle or joint pain, lowered white blood cell count, increased liver enzymes, and a potential immune system response to the virus that causes COVID-19[2]. But don't sweat it too much, as many of these side effects are temporary and should resolve over time.
less than 40 kg (about 88 pounds [lb])
But hey, stay vigilant, because Voranigo can also trigger more severe side effects, like liver problems and seizures. If you suspect you're experiencing either of these, get in touch with your doc ASAP.
20 mg once per day
Voranigo: The Brain Tumor Basher
Voranigo is approved to treat grade 2 astrocytoma and oligodendroglioma tumors with IDH1 or IDH2 mutations in people 12 years and older. It belongs to a group of brain tumors called gliomas, which originate in different types of brain cells (astrocytes or oligodendrocytes). Grade 2 gliomas are typically slower-growing tumors, but they can still spread to nearby brain tissue.
40 kg or more
The FDA approved Voranigo specifically for tumors that have an IDH1 or IDH2 mutation in their cells[3]. Before starting treatment, your healthcare provider will likely take a biopsy sample from the tumor to confirm the presence of this mutation.
40 mg once per day
So, what's the dosage, buddy? The recommended daily dosage for adults is 40 mg once per day, while the dosage for children varies based on weight:
- Less than 40 kg (about 88 lbs): 20 mg once per day
- 40 kg or more: 40 mg once per day
Regarding the proper administration of Voranigo, you can take it with or without food. Swallow the tablets whole with water and, if you're struggling with swallowing, chat with your pharmacist or doc about other options.
And of course, nothing's perfect...what about potential drug interactions? Voranigo can interfere with a variety of medications, pill forms of birth control, and other drugs[4]. To avoid any unwanted interactions, always inform your healthcare provider about all the meds, vitamins, herbs, and supplements you're using before starting treatment with Voranigo.
• ciprofloxacin (Cipro)• cyclosporine (Neoral, others)• fluvoxamine (Luvox)• phenytoin (Dilantin, Phenytek)• rifampin (Rifadin, Rimatane)• hormonal forms of birth control, such as the combined pill, minipill, or patch
Remember, Voranigo isn't the right choice for everyone. Consult your healthcare provider if you have concerns about potential interactions or if you have liver or kidney problems, previous allergic reactions to similar medications, are pregnant, breastfeeding, or a smoker.
Stay Informed, Stay Healthy
It is always important to remain well-informed about the drugs you're taking and discuss any potential side effects, drug interactions, or concerns with your healthcare provider. When it comes to treating cancer, having all the info and making informed decisions about your treatment options is essential. So, talk to your doc and don't be afraid to ask questions. 🤘🚀
References:
[1] https://www.fda.gov/news-events/press-announcements/fda-approves-vorasidenib-voranigo-treat-patients-certain-brain-tumors
[2] https://www.drugs.com/sfx/voranigo-side-effects.html
[3] https://www.fda.gov/drugs/resources-information-approved-drugs/post-market-drug-safety-information-patients-and-providers
[4] https://glioblastomastemcells.com/voranigo- astronov-6/
- Voranigo, a brain tumor-busting solution, is primarily used for grade 2 astrocytoma or oligodendroglioma with specific genetic mutations (IDH1 or IDH2).
- However, it's important to note that Voranigo is not available as a generic drug yet, so patients may not see any price drops from copycat medications.
- The cost of Voranigo can vary depending on factors like insurance, location, and pharmacy, but a program called ServierONE offers copay cards to help with the financial burden.
- Side effects from Voranigo can range from mild (such as fatigue, headache, and nausea) to severe (like liver problems and seizures).
- It's crucial for patients to discuss potential side effects, drug interactions, and concerns about Voranigo with their healthcare provider to make informed decisions about their treatment options.
