Bacterial aging and division processes could be significantly distinct from our current understanding!
In a groundbreaking study, biologists at the University of California San Diego have challenged the long-held belief that bacteria do not age in the same way as other living organisms. The study, which observed thousands of generations of E. coli bacteria, provides evidence that these bacteria may age through the accumulation of non-genetic damage.
According to the research, E. coli bacteria undergo an active sorting system during division, transferring non-genetic damage to one daughter cell, often referred to as the 'aged' one. The other half of the dividing E. coli cell, on the other hand, starts with a new, less damaged state. This process is known as "rejuvenation" or "asymmetric cell division."
When E. coli bacteria divide, they grow to different sizes. Computer models indicate that more damage is transferred to one half of the dividing E. coli cell, giving an evolutionary advantage to the other half. The growth difference between the resulting bacteria over time suggests that E. coli division is not even. This asymmetry drives evolution, as one half survives with more damage and the other becomes more robust.
The study, which builds upon earlier work from 2005 and 2010, found that bacteria use aging characteristics to alter the reproductive abilities of older and younger individuals. The more detailed and sophisticated 2010 study, however, suggested that bacteria do not age. This new study challenges that notion, suggesting that bacteria do age, but in a unique way that allows for survival and evolution.
The 2005 study showed signs of aging in bacteria, and this new research further supports that idea. If E. coli division were symmetric, there would be no survival due to the accumulation of non-genetic damage. However, the asymmetry in E. coli division ensures that one half can survive and reproduce, while the other becomes more robust.
This finding has significant implications for our understanding of bacterial behaviour and evolution. Bacterial cells can divide repeatedly, resulting in populations that never cease to grow. However, this new research suggests that the survival of the fittest may not be as straightforward as previously thought, with aging and asymmetric division playing a crucial role in the evolution of E. coli bacteria.
In conclusion, the study conducted by UC San Diego biologists provides compelling evidence that E. coli bacteria age through the accumulation of non-genetic damage and that this aging process is driven by asymmetric cell division. This new understanding of bacterial aging and division could lead to a better understanding of how bacteria evolve and adapt to their environments.
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